Hair problems may be due to cosmetic causes, such as use of harsh shampoos and blow-drying,
or due to underlying diseases, such as thyroid problems but the inherent cause is
Allergy.
CONCEPT OF ALLERGY
Allergy (Greek: allos, other + ergon, work = altered reaction) is an abnormal and
individual hypersensitivity to substances that are ordinarily harmless and which
result in various types of reactions. Pollens, for example, are generally harmless,
yet many people are acutely sensitive or allergic to their presence.
WHY DOES A PERSON DEVELOP ALLERGY?
Normally, a person’s immune system clearly distinguishes between harmful and harmless
foreign bodies and it reacts only to harmful bodies like various pathogenic bacteria
and virus. When immune system fails to recognize harmless bodies as ”harmless” it
reacts to it and produces various symptoms in the form of allergic manifestations.
MECHANISM OF ALLERGIC RESPONSE
When an allergen enters our body, the IgE and the allergen forms a complex. This
complex then binds to the mast cell. As a result, the mast cell bursts and releases
histamine. This histamine produces the allergic symptoms such as redness, swelling,
heat, itching etc.
TYPES OF ALLERGY
Exogenic allergy is caused by various external allergens like industrial wastes,
chemicals, insecticides, pesticides etc. Eventually, all allergens seem to cause
gradual changes in the genetic make up and subsequently the allergy becomes Endogenic.
The body tissues get ’sensitized’ to various allergens and this leads to
hypersensitivity reactions. These ’sensitized’ response characteristics are passed
on to the succeeding generations.
The fundamental cause of all allergies, therefore, is endogenic and in most cases
it runs in the family tree of the patient.
Often allergy remains dormant in the patient’s body system until a situation arises
when the patient’s immune system is at low guard and his resistance is highly compromised.
’Physical stress states’ such as surgery, infections, serious diseases, pregnancy,
old age etc. are some of the conditions because of which body gets predisposed to
attacks by allergens.
Some of the commonest allergic diseases alternate in a patient’s life. A patient
suffering from eczema in childhood may suffer from Bronchial Asthma in adulthood.
Usually there would be a history of Hay fever, Urticaria, Eczema, Asthma, Arthritis
etc. in the family. Similarly hair problems, an allergic manifestation of skin,
also have a genetic base and present with an inflammatory response as elucidated
below.
Core Pathology in Hair loss - Inflammation: After puberty, Testosterone typically
increases in the overall blood supply of most males. When DHT (Dihydrotestosterone)
and the Androgen receptors are in normal abundance, binding at normal rates, hair
growth regulation is also normal. Hair grows and falls, as it should. The overabundance
however, throws the whole process off the track.
The process described above initiates what is called an autoimmune response.
Follicles experiencing this are suddenly considered foreign objects in the body,
and the degradation is a direct result of the body rejecting them from the system.
This is really what Male Pattern Baldness is all about.
One of the biggest signs of the autoimmune response is tingling, itching, redness,
and inflammation of the scalp. Not all men losing hair experience this, but a vast
majority does. Inflammation is considered as one of the other major factors, which
exacerbate the hair loss process. This further consolidates the concept of Allergy.